Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D01UTX
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| Drug Name |
PMID25656651-Compound-31c
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| Drug Type |
Small molecular drug
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| Company |
NOVARTIS AG BURGER, Matthew DING, Yu HAN, Wooseok LINDVALL, Mika NISHIGUCHI, Gisele A. RICO, Alice SMITH, Aaron TANNER, Huw WAN, Lifeng
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| Structure |
 |
Download2D MOL |
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| Formula |
C25H27N5O4
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| Canonical SMILES |
C1CCC2(C(C1)OC(CC2O)C3=C(C=NC=C3)NC(=O)C4=NC(=CN=C4N)C5=CC=CC=C5)O
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| InChI |
1S/C25H27N5O4/c26-23-22(29-17(14-28-23)15-6-2-1-3-7-15)24(32)30-18-13-27-11-9-16(18)19-12-20(31)25(33)10-5-4-8-21(25)34-19/h1-3,6-7,9,11,13-14,19-21,31,33H,4-5,8,10,12H2,(H2,26,28)(H,30,32)/t19-,20-,21-,25+/m1/s1
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| InChIKey |
MHELWFWYAKEXOQ-YCFYUYSTSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Fusion protein Bcr-Abl T315I mutant (Bcr-Abl T315I) | Target Info | Inhibitor | [1] |
| Target's Patent Info | Fusion protein Bcr-Abl T315I mutant (Bcr-Abl T315I) | Target's Patent Info | [1] | |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Bcr-Abl tyrosine kinase inhibitors: a patent review.Expert Opin Ther Pat. 2015 Apr;25(4):397-412. | |||
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