Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D01TWD
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| Former ID |
DNC006761
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| Drug Name |
3-tapap
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| Synonyms |
3-Tapap; TAPAP; AC1Q5K4B; AC1L2Q7B; Nalpha-Tosyl-(3-amidinophenyl)alanine piperidide; N(alpha)-(4-Toluenesulfonyl)-3-amidinophenylalanylpiperidine; CHEMBL384295; 80457-09-6; 3-[2-{[(4-methylphenyl)sulfonyl]amino}-3-oxo-3-(piperidin-1-yl)propyl]benzenecarboximidamide; 1-(3-(3-(Aminoiminomethyl)phenyl)-2-(((4-methylphenyl)sulfonyl)amino)-1-oxopropyl)piperidine; Piperidine, 1-(3-(3-(aminoiminomethyl)phenyl)-2-(((4-methylphenyl)sulfonyl)amino)-1-oxopropyl)-; 73438-63-8; N(alpha)-Tosyl-(3-amidinophenyl)alanine piperidide
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C22H28N4O3S
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| Canonical SMILES |
CC1=CC=C(C=C1)S(=O)(=O)NC(CC2=CC(=CC=C2)C(=N)N)C(=O)N3CCCCC3
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| InChI |
1S/C22H28N4O3S/c1-16-8-10-19(11-9-16)30(28,29)25-20(22(27)26-12-3-2-4-13-26)15-17-6-5-7-18(14-17)21(23)24/h5-11,14,20,25H,2-4,12-13,15H2,1H3,(H3,23,24)
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| InChIKey |
RNNMXTSTLVYYQG-UHFFFAOYSA-N
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| CAS Number |
CAS 73438-63-8
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Suppressor of tumorigenicity 14 protein (ST14) | Target Info | Inhibitor | [1] |
| KEGG Pathway | MicroRNAs in cancer | |||
| NetPath Pathway | TCR Signaling Pathway | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Secondary amides of sulfonylated 3-amidinophenylalanine. New potent and selective inhibitors of matriptase. J Med Chem. 2006 Jul 13;49(14):4116-26. | |||
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