Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D01PJR
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| Former ID |
DAP000517
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| Drug Name |
Tocainide
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| Synonyms |
Taquidil; Tocainida; Tocainidum; Tonocard; Astra W 36095; Tocainida [INN-Spanish]; Tocainidum [INN-Latin]; W-36095; Tocainide (USAN/INN); Tocainide [USAN:BAN:INN]; Alanyl-2,6-xylidide; N-(2,6-dimethylphenyl)alaninamide; (-)-2-Amino-N-(2,6-dimethylphenyl)propanamide; 2-AMINO-N-(2,6-DIMETHYLPHENYL)PROPANAMIDE; 2-Amino-2',6'-propionoxylidide; 2-Amino-N-(2,6-dimethylphenyl)propionamid
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| Drug Type |
Small molecular drug
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| Indication | Ventricular arrhythmias [ICD-11: BC71; ICD-10: I49, I49.8; ICD-9: 427.1] | Approved | [1], [2] | |
| Therapeutic Class |
Antiarrhythmic Agents
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| Structure |
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Download2D MOL |
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| Formula |
C11H16N2O
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| Canonical SMILES |
CC1=C(C(=CC=C1)C)NC(=O)C(C)N
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| InChI |
1S/C11H16N2O/c1-7-5-4-6-8(2)10(7)13-11(14)9(3)12/h4-6,9H,12H2,1-3H3,(H,13,14)
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| InChIKey |
BUJAGSGYPOAWEI-UHFFFAOYSA-N
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| CAS Number |
CAS 41708-72-9
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| PubChem Compound ID | ||||
| PubChem Substance ID |
9351, 6596767, 7980808, 8175799, 11467055, 11468175, 11486810, 14797358, 26719896, 26755668, 34704899, 46386772, 46505385, 47207830, 47647789, 47945105, 48095800, 48170709, 49681729, 49699394, 50025969, 50111018, 50209485, 56313712, 56459344, 57312259, 85788915, 90341559, 92308356, 92714653, 92729958, 103990696, 104234273, 104330445, 117572998, 119526024, 124658847, 124800068, 125536952, 126623963, 127569462, 134337809, 135002146, 135111575, 135251693, 137231400, 142472715, 145355976, 160964390, 162022110
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| ChEBI ID |
CHEBI:9611
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| SuperDrug ATC ID |
C01BB03
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| SuperDrug CAS ID |
cas=041708729
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Voltage-gated sodium channel (Nav) | Target Info | Modulator | [3] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7309). | |||
| REF 2 | FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (NDA) 018257. | |||
| REF 3 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. | |||
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