Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D01NCH
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| Former ID |
DIB015007
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| Drug Name |
Lufironil
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| Synonyms |
Hoe-077
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| Drug Type |
Small molecular drug
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| Indication | Liver cirrhosis [ICD-11: DB93.1] | Phase 2 | [1] | |
| Company |
Hoechst AG
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| Structure |
 |
Download2D MOL |
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| Formula |
C13H19N3O4
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| Canonical SMILES |
COCCNC(=O)C1=CC(=NC=C1)C(=O)NCCOC
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| InChI |
1S/C13H19N3O4/c1-19-7-5-15-12(17)10-3-4-14-11(9-10)13(18)16-6-8-20-2/h3-4,9H,5-8H2,1-2H3,(H,15,17)(H,16,18)
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| InChIKey |
JUCNGMPTCXPMNB-UHFFFAOYSA-N
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| CAS Number |
CAS 128075-79-6
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Prolyl 4-hydroxylasesubunit alpha-1 (P4HA1) | Target Info | Modulator | [1], [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Interference in clinical laboratory tests, with special regard to the bilirubin assay: effects of a metabolite of the new prolyl 4-hydroxylase inhibitor, Lufironil. Eur J Clin Chem Clin Biochem. 1994Jul;32(7):515-20. | |||
| REF 2 | Antifibrogenic therapies in chronic HCV infection. Curr Drug Targets Infect Disord. 2001 Aug;1(2):227-40. | |||
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