Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D01NBX
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| Former ID |
DIB013593
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| Drug Name |
RS-2135
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| Synonyms |
(+)-RS-2135; 133775-36-7
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| Drug Type |
Small molecular drug
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| Indication | Heart arrhythmia [ICD-11: BC65; ICD-10: I49, I49.8] | Terminated | [1] | |
| Company |
Sankyo Co Ltd
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| Structure |
 |
Download2D MOL |
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| Formula |
C18H21ClN2O2
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| Canonical SMILES |
C1CC2CC(=O)N3C4=C(C5=C3C2C(C1)C(C5)N)C(=CC=C4)O.Cl
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| InChI |
1S/C18H20N2O2.ClH/c19-12-8-11-17-13(5-2-6-14(17)21)20-15(22)7-9-3-1-4-10(12)16(9)18(11)20;/h2,5-6,9-10,12,16,21H,1,3-4,7-8,19H2;1H/t9-,10+,12-,16+;/m1./s1
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| InChIKey |
MTSROZWZVOQAQW-PECACPRSSA-N
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| CAS Number |
CAS 133775-36-7
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Sodium channel unspecific (NaC) | Target Info | Modulator | [2] |
| KEGG Pathway | Dopaminergic synapse | |||
| Reactome | Interaction between L1 and Ankyrins | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800001212) | |||
| REF 2 | Electrophysiologic effects of RS-2135, a new antiarrhythmic compound, on canine Purkinje fibers. J Cardiovasc Pharmacol. 1992 Dec;20(6):955-60. | |||
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