Drug Information
Drug General Information | Top | |||
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Drug ID |
D01MWX
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Former ID |
DNC009239
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Drug Name |
2,7-Bis(cyclopropanecarbonamido)anthraquinone
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Synonyms |
2,7-Bis(cyclopropanecarbonamido)anthraquinone; CHEMBL520920; SCHEMBL4296357
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C22H18N2O4
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Canonical SMILES |
C1CC1C(=O)NC2=CC3=C(C=C2)C(=O)C4=C(C3=O)C=C(C=C4)NC(=O)C5CC5
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InChI |
1S/C22H18N2O4/c25-19-15-7-5-13(23-21(27)11-1-2-11)9-17(15)20(26)18-10-14(6-8-16(18)19)24-22(28)12-3-4-12/h5-12H,1-4H2,(H,23,27)(H,24,28)
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InChIKey |
SCYQIQINYUMLPD-UHFFFAOYSA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | TERT messenger RNA (TERT mRNA) | Target Info | Inhibitor | [1] |
KEGG Pathway | HTLV-I infection | |||
NetPath Pathway | IL2 Signaling Pathway | |||
Pathway Interaction Database | Validated targets of C-MYC transcriptional activation | |||
Regulation of Telomerase | ||||
IL2 signaling events mediated by PI3K | ||||
Regulation of nuclear beta catenin signaling and target gene transcription | ||||
HIF-1-alpha transcription factor network | ||||
Reactome | Formation of the beta-catenin:TCF transactivating complex | |||
WikiPathways | TGF beta Signaling Pathway | |||
miR-targeted genes in lymphocytes - TarBase | ||||
miR-targeted genes in epithelium - TarBase | ||||
Telomere Maintenance |
References | Top | |||
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REF 1 | Synthesis, human telomerase inhibition and anti-proliferative studies of a series of 2,7-bis-substituted amido-anthraquinone derivatives. Bioorg Med Chem. 2008 Jul 15;16(14):6976-86. |
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