Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D01KTM
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| Former ID |
DNC007380
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| Drug Name |
(-)-pinoresinol
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| Synonyms |
Pinoresinol; NSC35444; NSC-35444; bmse010297; AC1Q70QC; (+/-)-PINORESINOL; SCHEMBL122106; AC1L5T18; CHEMBL2252392; CTK2H0032; 4,4'-[(1S,3aR,4S,6aR)-Tetrahydro-1H,3H-furo[3,4-c]furan-1,4-diyl]bis(2-methoxyphenol); HMS3347E17; AKOS025404740; 4,4'-tetrahydro-1H,3H-furo[3,4-c]furan-1,4-diylbis(2-methoxyphenol); phenol, 4,4'-(tetrahydro-1H,3H-furo[3,4-c]furan-1,4-diyl)bis[2-methoxy-; Phenol,4'-(tetrahydro-1H,3H-furo[3,4-c]furan-1,4-diyl)bis[2-methoxy-, [1S-(1.alpha.,3a.alpha.,4.alpha.,6a.alpha.)]-
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C20H22O6
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| Canonical SMILES |
COC1=C(C=CC(=C1)C2C3COC(C3CO2)C4=CC(=C(C=C4)O)OC)O
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| InChI |
1S/C20H22O6/c1-23-17-7-11(3-5-15(17)21)19-13-9-26-20(14(13)10-25-19)12-4-6-16(22)18(8-12)24-2/h3-8,13-14,19-22H,9-10H2,1-2H3/t13-,14-,19+,20+/m1/s1
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| InChIKey |
HGXBRUKMWQGOIE-NSMLZSOPSA-N
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| PubChem Compound ID | ||||
| ChEBI ID |
CHEBI:67245
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Arachidonate 15-lipoxygenase (15-LOX) | Target Info | Inhibitor | [1] |
| LOX-5 messenger RNA (ALOX5 mRNA) | Target Info | Inhibitor | [1] | |
| BioCyc | Resolvin D biosynthesis | |||
| Lipoxin biosynthesis | ||||
| Aspirin-triggered lipoxin biosynthesis | ||||
| Leukotriene biosynthesis | ||||
| Aspirin triggered resolvin D biosynthesis | ||||
| Aspirin triggered resolvin E biosynthesis | ||||
| KEGG Pathway | Arachidonic acid metabolism | |||
| Linoleic acid metabolism | ||||
| Metabolic pathways | ||||
| Serotonergic synapse | ||||
| Ovarian steroidogenesis | ||||
| Toxoplasmosis | ||||
| NetPath Pathway | IL4 Signaling Pathway | |||
| Panther Pathway | Inflammation mediated by chemokine and cytokine signaling pathway | |||
| Pathwhiz Pathway | Arachidonic Acid Metabolism | |||
| Pathway Interaction Database | IL4-mediated signaling events | |||
| WikiPathways | Arachidonic acid metabolism | |||
| Eicosanoid Synthesis | ||||
| Selenium Micronutrient Network | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Lipoxygenase inhibitory constituents of the fruits of noni (Morinda citrifolia) collected in Tahiti. J Nat Prod. 2007 May;70(5):859-62. | |||
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