Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D01JEX
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| Former ID |
DNC009536
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| Drug Name |
ROSETTACIN
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| Synonyms |
ROSETTACIN; SCHEMBL4374000; CHEMBL110203; ZINC26972929
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C19H12N2O
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| Canonical SMILES |
C1C2=CC3=CC=CC=C3N=C2C4=CC5=CC=CC=C5C(=O)N41
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| InChI |
1S/C19H12N2O/c22-19-15-7-3-1-5-12(15)10-17-18-14(11-21(17)19)9-13-6-2-4-8-16(13)20-18/h1-10H,11H2
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| InChIKey |
JORFMKUBMHCFKA-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | DNA topoisomerase I (TOP1) | Target Info | Inhibitor | [1] |
| NetPath Pathway | IL2 Signaling Pathway | |||
| Panther Pathway | DNA replication | |||
| Pathway Interaction Database | Caspase Cascade in Apoptosis | |||
| WikiPathways | Integrated Pancreatic Cancer Pathway | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Synthesis and biological evaluation of 14-(aminoalkyl-aminomethyl)aromathecins as topoisomerase I inhibitors: investigating the hypothesis of share... Bioorg Med Chem. 2009 Oct 15;17(20):7145-55. | |||
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