Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D01HCL
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| Former ID |
DIB018475
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| Drug Name |
13,14-dihydro-PGE1
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| Synonyms |
13,14-dihydro-prostaglandin E1
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL
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| Formula |
C20H36O5
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| Canonical SMILES |
CCCCCC(CCC1C(CC(=O)C1CCCCCCC(=O)O)O)O
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| InChI |
1S/C20H36O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h15-17,19,21,23H,2-14H2,1H3,(H,24,25)/t15-,16+,17+,19+/m0/s1
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| InChIKey |
DPOINJQWXDTOSF-DODZYUBVSA-N
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| CAS Number |
CAS 19313-28-1
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| PubChem Compound ID | ||||
| PubChem Substance ID |
4266060, 10254406, 11120196, 11120684, 11121172, 11121394, 11121874, 11147279, 11362463, 11365025, 11367587, 11370197, 11370198, 11373188, 11375749, 26754838, 26754839, 46236146, 47440002, 47440003, 50110798, 57278192, 57349451, 77504584, 92309745, 99300659, 99302177, 103097584, 103097585, 104046456, 113446651, 126524627, 127768583, 131342665, 134224789, 135116858, 135651374, 142826069, 179205586, 231313899, 242279203, 251966034, 252455469, 252457185, 252464034
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| ChEBI ID |
CHEBI:89310
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Prostaglandin E2 receptor EP4 (PTGER4) | Target Info | Agonist | [2] |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Inflammatory mediator regulation of TRP channels | ||||
| Renin secretion | ||||
| Pathways in cancer | ||||
| NetPath Pathway | FSH Signaling Pathway | |||
| IL2 Signaling Pathway | ||||
| IL4 Signaling Pathway | ||||
| TGF_beta_Receptor Signaling Pathway | ||||
| Reactome | Prostanoid ligand receptors | |||
| G alpha (s) signalling events | ||||
| WikiPathways | Prostaglandin Synthesis and Regulation | |||
| GPCRs, Class A Rhodopsin-like | ||||
| Vitamin D Receptor Pathway | ||||
| Small Ligand GPCRs | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1946). | |||
| REF 2 | Pharmacological characterization of [(3)H]-prostaglandin E(2) binding to the cloned human EP(4) prostanoid receptor. Br J Pharmacol. 2000 Aug;130(8):1919-26. | |||
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