Drug Information
Drug General Information | Top | |||
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Drug ID |
D01EVE
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Former ID |
DIB019590
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Drug Name |
PMID25703523C7d
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Synonyms |
43U; GTPL8304
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1], [2] | |
Structure |
Download2D MOL
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Formula |
C12H10BrN5O
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Canonical SMILES |
COC1=C(C=C(C=C1)Br)C2=C3C(=NC(=N2)N)N=CN3
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InChI |
1S/C12H10BrN5O/c1-19-8-3-2-6(13)4-7(8)9-10-11(16-5-15-10)18-12(14)17-9/h2-5H,1H3,(H3,14,15,16,17,18)
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InChIKey |
KDNVOUMYSICLPF-UHFFFAOYSA-N
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PubChem Compound ID | ||||
PubChem Substance ID |
Target and Pathway | Top | |||
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Target(s) | Bromodomain-containing protein 4 (BRD4) | Target Info | Inhibitor | [1] |
WikiPathways | Chemical Compounds to monitor Proteins |
References | Top | |||
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REF 1 | 9H-purine scaffold reveals induced-fit pocket plasticity of the BRD9 bromodomain. J Med Chem. 2015 Mar 26;58(6):2718-36. | |||
REF 2 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 8304). |
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