Drug Information
Drug General Information | Top | |||
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Drug ID |
D01DSB
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Former ID |
DIB007043
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Drug Name |
VTX-744
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Synonyms |
VTX-744 (adjuvant, vaccination), VentiRx
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Company |
VentiRx Pharmaceuticals Inc
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Target and Pathway | Top | |||
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Target(s) | Toll-like receptor 8 (TLR8) | Target Info | Modulator | [1] |
KEGG Pathway | Toll-like receptor signaling pathway | |||
NetPath Pathway | Leptin Signaling Pathway | |||
TCR Signaling Pathway | ||||
Panther Pathway | Toll receptor signaling pathway | |||
Reactome | Trafficking and processing of endosomal TLR | |||
TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling | ||||
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation | ||||
MyD88 dependent cascade initiated on endosome | ||||
WikiPathways | Toll-like receptor signaling pathway | |||
Toll-Like Receptors Cascades | ||||
MyD88 dependent cascade initiated on endosome | ||||
Trafficking and processing of endosomal TLR | ||||
Regulation of toll-like receptor signaling pathway |
References | Top | |||
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REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1758). |
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