Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D01DMS
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| Former ID |
DIB018108
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| Drug Name |
(S)-5-iodowillardiine
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| Synonyms |
IODO-WILLARDIINE; S-5-Iodowillardiine; (S)-(-)-5-IODOWILLARDIINE; (s)-5-iodowillardiine; 140187-25-3; CHEMBL121915; 2-AMINO-3-(5-IODO-2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-PROPIONIC ACID; IWD; 5 Iodowillardine; 5-iodowillardiine; 1mqg; Tocris-0307; AC1L9KKQ; Lopac0_001239; SCHEMBL401659; GTPL4071; SCHEMBL13319969; DTXSID90332246; MolPort-006-069-040; ZINC2047688; BDBM50060627; AKOS024457411; DB02818; CCG-205313; NCGC00024529-01; NCGC00024529-02; EU-0101239; B6252; W-110; SR-01000597629; SR-01000075424; SR-01000075424-1; J-007367
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL
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| Formula |
C7H8IN3O4
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| Canonical SMILES |
C1=C(C(=O)NC(=O)N1CC(C(=O)O)N)I
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| InChI |
1S/C7H8IN3O4/c8-3-1-11(2-4(9)6(13)14)7(15)10-5(3)12/h1,4H,2,9H2,(H,13,14)(H,10,12,15)/t4-/m0/s1
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| InChIKey |
AXXYLTBQIQBTES-BYPYZUCNSA-N
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| CAS Number |
CAS 140187-25-3
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| PubChem Compound ID | ||||
| PubChem Substance ID |
7888500, 7978602, 10300013, 11113440, 17405793, 36889416, 46392539, 46506600, 47589096, 50104371, 53778345, 77583035, 92303223, 103349493, 103956304, 104637646, 123120882, 124750346, 124807303, 135698123, 136973113, 137124784, 140862565, 144220286, 152137876, 160965981, 170485611, 178100894, 226730173, 238317508, 241034603, 241181610, 241376244, 243324007
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Glutamate receptor ionotropic kainate 1 (GRIK1) | Target Info | Agonist | [2] |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Glutamatergic synapse | ||||
| Panther Pathway | Huntington disease | |||
| Ionotropic glutamate receptor pathway | ||||
| Metabotropic glutamate receptor group III pathway | ||||
| Metabotropic glutamate receptor group I pathway | ||||
| WikiPathways | Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4071). | |||
| REF 2 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 450). | |||
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