Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D01DMN
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| Former ID |
DIB021232
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| Drug Name |
XD1
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| Synonyms |
colchicein; colchiceine; NSC33411
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL
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| Formula |
C21H23NO6
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| Canonical SMILES |
CC(=O)NC1CCC2=CC(=C(C(=C2C3=CC=C(C(=O)C=C13)O)OC)OC)OC
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| InChI |
1S/C21H23NO6/c1-11(23)22-15-7-5-12-9-18(26-2)20(27-3)21(28-4)19(12)13-6-8-16(24)17(25)10-14(13)15/h6,8-10,15H,5,7H2,1-4H3,(H,22,23)(H,24,25)/t15-/m0/s1
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| InChIKey |
PRGILOMAMBLWNG-HNNXBMFYSA-N
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| CAS Number |
CAS 477-27-0
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| PubChem Compound ID | ||||
| PubChem Substance ID |
91563, 416872, 8138156, 9385595, 11113260, 11342098, 11362281, 11363251, 11365813, 11368375, 11372340, 11374183, 11376537, 11407317, 11483968, 11487683, 11488112, 11490976, 11492397, 11494171, 11537929, 16416647, 26612982, 26680519, 26754308, 30033540, 47647536, 48394928, 50123146, 52008917, 57400232, 85149166, 91010721, 103385315, 103821584, 104044472, 104455138, 108657815, 117570090, 118246378, 124558809, 124637682, 124791058, 124883062, 124883063, 143217090, 162259024, 165277809, 172096899, 179039729
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Bromodomain-containing protein 4 (BRD4) | Target Info | Inhibitor | [2] |
| WikiPathways | Chemical Compounds to monitor Proteins | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7525). | |||
| REF 2 | 4-Acyl pyrroles: mimicking acetylated lysines in histone code reading. Angew Chem Int Ed Engl. 2013 Dec 23;52(52):14055-9. | |||
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