Drug Information
Drug General Information | Top | |||
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Drug ID |
D01DDN
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Former ID |
DNCL001886
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Drug Name |
SCH-900271
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Synonyms |
SCH-900271; UNII-G2283XQ6VJ; SCH 900271; G2283XQ6VJ; 915210-50-3; CHEMBL2036958; GTPL8469; SCHEMBL12602910; DTXSID00238609; BDBM50384612; SCH900271; SB17408; DB12433; 2H-Pyrano(2,3-d)pyrimidine-2,4,7(1H,3h)-trione, 5-(3-(1-methylcyclopropyl)propyl)-; 5-(3-(1-Methylcyclopropyl)propyl)-1H-pyrano(2,3-d)pyrimidine-2,4,7(3H)-trione
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Drug Type |
Small molecular drug
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Indication | Ischemic stroke [ICD-11: 8B11.5Z; ICD-9: 434.91] | Phase 2 | [1], [2] | |
Company |
Merck
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Structure |
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Download2D MOL
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Formula |
C14H16N2O4
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Canonical SMILES |
CC1(CC1)CCCC2=CC(=O)OC3=C2C(=O)NC(=O)N3
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InChI |
1S/C14H16N2O4/c1-14(5-6-14)4-2-3-8-7-9(17)20-12-10(8)11(18)15-13(19)16-12/h7H,2-6H2,1H3,(H2,15,16,18,19)
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InChIKey |
ARJKMWXLIHZLQZ-UHFFFAOYSA-N
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CAS Number |
CAS 915210-50-3
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PubChem Compound ID | ||||
PubChem Substance ID |
Target and Pathway | Top | |||
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Target(s) | Nicotinic acid receptor (HCAR2) | Target Info | Modulator | [2] |
References | Top | |||
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REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 8469). | |||
REF 2 | Discovery of SCH 900271, a Potent Nicotinic Acid Receptor Agonist for the Treatment of Dyslipidemia. ACS Med Chem Lett. 2011 Nov 24;3(1):63-8. |
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