Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D01BCQ
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| Former ID |
DNC011384
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| Drug Name |
Divaplon
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| Synonyms |
Divaplon; 90808-12-1; UNII-4AOV43246G; 4AOV43246G; Divaplonum; Divaplone; methanone,(6-ethyl-7-methoxy-5-methylimidazo[1,2-a]pyrimidin-2-yl)phenyl-; Divaplon [INN]; Divaplonum [INN-Latin]; Divaplone [INN-French]; SCHEMBL678101; CHEMBL281164; ZINC1325; DTXSID40238269; AC1L2418; RU-32698; KB-274411; 6-Ethyl-7-methoxy-5-methylimidazo(1,2-a)pyrimidin-2-yl phenyl ketone; (6-ethyl-7-methoxy-5-methylimidazo[1,2-a]pyrimidin-2-yl)-phenylmethanone; Methanone, (6-ethyl-7-methoxy-5-methylimidazo(1,2-a)pyrimidin-2-yl)phenyl-
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| Drug Type |
Small molecular drug
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| Structure |
 |
Download2D MOL |
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| Formula |
C17H17N3O2
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| Canonical SMILES |
CCC1=C(N2C=C(N=C2N=C1OC)C(=O)C3=CC=CC=C3)C
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| InChI |
1S/C17H17N3O2/c1-4-13-11(2)20-10-14(18-17(20)19-16(13)22-3)15(21)12-8-6-5-7-9-12/h5-10H,4H2,1-3H3
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| InChIKey |
NRJVHCSYLGLURI-UHFFFAOYSA-N
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| CAS Number |
CAS 90808-12-1
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | GABA(A) receptor alpha-1 (GABRA1) | Target Info | Inhibitor | [1] |
| Gamma-aminobutyric acid receptor (GAR) | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Retrograde endocannabinoid signaling | ||||
| GABAergic synapse | ||||
| Morphine addiction | ||||
| Nicotine addiction | ||||
| Reactome | Ligand-gated ion channel transport | |||
| GABA A receptor activation | ||||
| WikiPathways | SIDS Susceptibility Pathways | |||
| Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell | ||||
| Iron uptake and transport | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | (Imidazo[1,2-a]pyrimidin-2-yl)phenylmethanones and related compounds as potential nonsedative anxiolytics. J Med Chem. 1988 Jun;31(6):1220-6. | |||
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