Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D00XCL
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| Former ID |
DNC009517
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| Drug Name |
1-(4-aminophenylsulfonyl)-3-(2-mercaptoethyl)urea
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| Synonyms |
CHEMBL497689; 4-Amino-N-[(2-Sulfanylethyl)carbamoyl]benzenesulfonamide; 1-(4-aminophenylsulfonyl)-3-(2-mercaptoethyl)urea; BDBM50272611; DB08484; 1-(4-aminobenzenesulfonyl)-3-(2-sulfanylethyl)urea
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C9H13N3O3S2
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| Canonical SMILES |
C1=CC(=CC=C1N)S(=O)(=O)NC(=O)NCCS
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| InChI |
1S/C9H13N3O3S2/c10-7-1-3-8(4-2-7)17(14,15)12-9(13)11-5-6-16/h1-4,16H,5-6,10H2,(H2,11,12,13)
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| InChIKey |
LHVDNDIAMJOEKH-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Fructose-1,6-bisphosphatase (FBP) | Target Info | Inhibitor | [1] |
| BioCyc | Gluconeogenesis | |||
| KEGG Pathway | Glycolysis / Gluconeogenesis | |||
| Pentose phosphate pathway | ||||
| Fructose and mannose metabolism | ||||
| Metabolic pathways | ||||
| Biosynthesis of antibiotics | ||||
| Carbon metabolism | ||||
| AMPK signaling pathway | ||||
| Insulin signaling pathway | ||||
| Glucagon signaling pathway | ||||
| Pathwhiz Pathway | Fructose and Mannose Degradation | |||
| Pentose Phosphate Pathway | ||||
| Gluconeogenesis | ||||
| Reactome | Gluconeogenesis | |||
| WikiPathways | Glycolysis and Gluconeogenesis | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Allosteric FBPase inhibitors gain 10(5) times in potency when simultaneously binding two neighboring AMP sites. Bioorg Med Chem Lett. 2008 Aug 15;18(16):4708-12. | |||
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