Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D00WVI
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| Former ID |
DIB015283
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| Drug Name |
AS-1907417
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| Synonyms |
AS-1535907; AS-1669058; AS-179009; GPR119 agonists (type 2 diabetes), Astellas Pharma
Click to Show/Hide
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| Drug Type |
Small molecular drug
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| Indication | Non-insulin dependent diabetes [ICD-11: 5A11] | Investigative | [1] | |
| Company |
Astellas Pharma Inc
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| Structure |
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Download2D MOL |
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| Formula |
C19H27N3O4S
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| Canonical SMILES |
C1CC(C1)C2=NC3=C(CS(=O)(=O)C3)C(=N2)N4CCC(CC4)CCCC(=O)O
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| InChI |
1S/C19H27N3O4S/c23-17(24)6-1-3-13-7-9-22(10-8-13)19-15-11-27(25,26)12-16(15)20-18(21-19)14-4-2-5-14/h13-14H,1-12H2,(H,23,24)
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| InChIKey |
NFFANIJTECFGGM-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Glucose-dependent insulinotropic receptor (GPR119) | Target Info | Agonist | [2] |
| KEGG Pathway | cAMP signaling pathway | |||
| Insulin secretion | ||||
| WikiPathways | Incretin Synthesis, Secretion, and Inactivation | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5723). | |||
| REF 2 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 126). | |||
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