Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D00TRV
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| Former ID |
DNAP001681
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| Drug Name |
Besifloxacin
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| Synonyms |
Besivance (TN)
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| Drug Type |
Small molecular drug
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| Indication | Ocular inflammation [ICD-11: 9C61.24; ICD-10: H40.4; ICD-9: 370.33] | Approved | [1], [2] | |
| Company |
Bausch & Lomb
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| Structure |
 |
Download2D MOL |
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| Formula |
C19H21ClFN3O3
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| Canonical SMILES |
C1CCN(CC(C1)N)C2=C(C=C3C(=C2Cl)N(C=C(C3=O)C(=O)O)C4CC4)F
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| InChI |
1S/C19H21ClFN3O3/c20-15-16-12(18(25)13(19(26)27)9-24(16)11-4-5-11)7-14(21)17(15)23-6-2-1-3-10(22)8-23/h7,9-11H,1-6,8,22H2,(H,26,27)/t10-/m1/s1
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| InChIKey |
QFFGVLORLPOAEC-SNVBAGLBSA-N
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| CAS Number |
CAS 141388-76-3
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| ChEBI ID |
CHEBI:135622
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| ADReCS Drug ID | BADD_D00256 | |||
| SuperDrug ATC ID |
S01AE08
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Bacterial DNA gyrase (Bact gyrase) | Target Info | Modulator | [1], [2] |
| Staphylococcus Topoisomerase IV (Stap-coc parC) | Target Info | Modulator | [1], [2] | |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Hughes B: 2009 FDA drug approvals. Nat Rev Drug Discov. 2010 Feb;9(2):89-92. | |||
| REF 2 | Besifloxacin ophthalmic suspension, 0.6%: a novel topical fluoroquinolone for bacterial conjunctivitis. Adv Ther. 2012 Jun;29(6):473-90. | |||
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