Drug Information
Drug General Information | Top | |||
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Drug ID |
D00RRB
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Drug Name |
Isoflavone derivative 1
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Synonyms |
PMID26666870-Compound-19
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Drug Type |
Small molecular drug
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Company |
UNIVERSITA' DEGLI STUDI DI SIENA,UNIVERSITA' DEGLI STUDI DI ROMA "LA SAPIENZA"
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Structure |
Download2D MOL |
Target and Pathway | Top | |||
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Target(s) | Smoothened homolog (SMO) | Target Info | Inhibitor | [1] |
Zinc finger protein GLI1 (Gli1) | Target Info | Inhibitor | [1] | |
Target's Patent Info | Smoothened homolog (SMO) | Target's Patent Info | [1] | |
Zinc finger protein GLI1 (Gli1) | Target's Patent Info | [1] | ||
KEGG Pathway | Hedgehog signaling pathway | |||
Pathways in cancer | ||||
Proteoglycans in cancer | ||||
Basal cell carcinoma | ||||
Panther Pathway | Hedgehog signaling pathway | |||
Pathway Interaction Database | Signaling events mediated by the Hedgehog family | |||
Hedgehog signaling events mediated by Gli proteins | ||||
Reactome | Class B/2 (Secretin family receptors) | |||
Hedgehog 'off' state | ||||
Activation of SMO | ||||
WikiPathways | Hedgehog Signaling Pathway | |||
Hair Follicle Development: Organogenesis (Part 2 of 3) | ||||
Hair Follicle Development: Induction (Part 1 of 3) | ||||
Integrated Pancreatic Cancer Pathway | ||||
GPCR ligand binding | ||||
GPCRs, Other |
References | Top | |||
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REF 1 | Evaluation of WO2014207069 A1: Multitarget Hedgehog pathway inhibitors and uses thereof.Expert Opin Ther Pat. 2016;26(4):529-35. |
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