Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D00RFZ
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| Former ID |
DIB004335
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| Drug Name |
PSI-6130
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| Synonyms |
R-1656; RO-4995855; Hepatitis C virus therapy, Pharmasset/Roche; PSI-6130-DP; PSI-6130-MP; PSI-6130-TP
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| Drug Type |
Small molecular drug
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| Indication | Hepatitis C virus infection [ICD-11: 1E51.1; ICD-10: B18.2] | Terminated | [1] | |
| Company |
Pharmasset Inc
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| Structure |
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Download2D MOL |
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| Formula |
C10H14FN3O4
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| Canonical SMILES |
CC1(C(C(OC1N2C=CC(=NC2=O)N)CO)O)F
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| InChI |
1S/C10H14FN3O4/c1-10(11)7(16)5(4-15)18-8(10)14-3-2-6(12)13-9(14)17/h2-3,5,7-8,15-16H,4H2,1H3,(H2,12,13,17)/t5-,7-,8-,10-/m1/s1
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| InChIKey |
NYPIRLYMDJMKGW-VPCXQMTMSA-N
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| CAS Number |
CAS 817204-33-4
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Hepatitis C virus RNA-directed RNA polymerase (HCV NS5B) | Target Info | Inhibitor | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800024904) | |||
| REF 2 | An efficient and diastereoselective synthesis of PSI-6130: a clinically efficacious inhibitor of HCV NS5B polymerase. J Org Chem. 2009 Sep 4;74(17):6819-24. | |||
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