Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D00RDS
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| Former ID |
DNC008446
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| Drug Name |
4-tert-butyl-N-(quinolin-3-yl)benzamide
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| Synonyms |
CHEMBL258917; 331850-72-7; 4-tert-butyl-N-(quinolin-3-yl)benzamide; AC1LGMQ4; Oprea1_306931; Oprea1_506548; SCHEMBL846396; CTK1B8678; DTXSID30355358; MolPort-001-496-766; ZINC302143; BDBM50376277; AKOS000637295; MCULE-9209807944; 4-tert-butyl-N-quinolin-3-ylbenzamide; 4-tert-Butyl-N-quinolin-3-yl-benzamide; BAS 00631860; ST45006323; [4-(tert-butyl)phenyl]-N-(3-quinolyl)carboxamide; Benzamide, 4-(1,1-dimethylethyl)-N-3-quinolinyl-
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C20H20N2O
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| Canonical SMILES |
CC(C)(C)C1=CC=C(C=C1)C(=O)NC2=CC3=CC=CC=C3N=C2
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| InChI |
1S/C20H20N2O/c1-20(2,3)16-10-8-14(9-11-16)19(23)22-17-12-15-6-4-5-7-18(15)21-13-17/h4-13H,1-3H3,(H,22,23)
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| InChIKey |
MUZWQZALZQTMBA-UHFFFAOYSA-N
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| CAS Number |
CAS 331850-72-7
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Transient receptor potential cation channel V1 (TRPV1) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Inflammatory mediator regulation of TRP channels | ||||
| NetPath Pathway | IL2 Signaling Pathway | |||
| Pathway Interaction Database | Trk receptor signaling mediated by the MAPK pathway | |||
| Trk receptor signaling mediated by PI3K and PLC-gamma | ||||
| Reactome | TRP channels | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | N-pyridin-3-yl- and N-quinolin-3-yl-benzamides: modulators of human vanilloid receptor 1 (TRPV1). Bioorg Med Chem Lett. 2008 Apr 15;18(8):2730-4. | |||
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