Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D00PLV
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| Former ID |
DAP001317
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| Drug Name |
Nitroprusside
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| Synonyms |
C07269; LS-187044
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| Drug Type |
Small molecular drug
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| Indication | Hypertension [ICD-11: BA00-BA04; ICD-9: 401] | Approved | [1] | |
| Therapeutic Class |
Antihypertensive Agents
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| Structure |
 |
Download2D MOL |
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| Formula |
C5FeN6O
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| Canonical SMILES |
[C-]#N.[C-]#N.[C-]#N.[C-]#N.[C-]#N.[N-]=O.[Fe+6]
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| InChI |
1S/5CN.Fe.NO/c5*1-2;;1-2/q5*-1;+6;-1
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| InChIKey |
CDLSWOALPINAJL-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| SuperDrug ATC ID |
C02DD01
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| SuperDrug CAS ID |
cas=015078281
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Inositol 1,4,5-trisphosphate receptor (ITPR) | Target Info | Antagonist | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (ANDA) 073465. | |||
| REF 2 | Prostacyclin and sodium nitroprusside inhibit the activity of the platelet inositol 1,4,5-trisphosphate receptor and promote its phosphorylation. J Biol Chem. 1996 Mar 8;271(10):5545-51. | |||
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