Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D00PJJ
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| Former ID |
DIB011252
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| Drug Name |
FK-614
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| Synonyms |
ATx08-001; ATx08-001); PPAR gamma agonist (oral, neuropathic pain), Aestus
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| Drug Type |
Small molecular drug
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| Indication | Type-2 diabetes [ICD-11: 5A11; ICD-9: 250] | Phase 2 | [1] | |
| Company |
Fujisawa Pharmaceutical Co Ltd; aestus therapeutics
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| Structure |
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Download2D MOL |
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| Formula |
C21H23Cl2N3O3S
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| Canonical SMILES |
CCCCCS(=O)(=O)NC(=O)C1=CC2=C(C=C1)N=C(N2CC3=C(C=C(C=C3)Cl)Cl)C
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| InChI |
1S/C21H23Cl2N3O3S/c1-3-4-5-10-30(28,29)25-21(27)15-7-9-19-20(11-15)26(14(2)24-19)13-16-6-8-17(22)12-18(16)23/h6-9,11-12H,3-5,10,13H2,1-2H3,(H,25,27)
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| InChIKey |
UYGZODVVDUIDDQ-UHFFFAOYSA-N
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| CAS Number |
CAS 193012-35-0
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| PubChem Compound ID | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | FK-614, a selective peroxisome proliferator-activated receptor gamma agonist, improves peripheral glucose utilization while decreasing hepatic insulin extraction in alloxan-induced diabetic dogs. Metabolism. 2005 Sep;54(9):1250-8. | |||
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