Drug Information
Drug General Information | Top | |||
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Drug ID |
D00OMV
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Former ID |
DNC012128
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Drug Name |
Arteminolide
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C35H42O8
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Canonical SMILES |
CC1=C2C(C3C(C(C1)OC(=O)CC(C)C)C4(CC56C=CC4(C5C7C(CCC6(C)O)C(=C)C(=O)O7)C)C(=O)O3)C(=CC2=O)C
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InChI |
1S/C35H42O8/c1-16(2)12-23(37)41-22-14-18(4)24-21(36)13-17(3)25(24)28-26(22)35(31(39)43-28)15-34-11-10-32(35,6)29(34)27-20(8-9-33(34,7)40)19(5)30(38)42-27/h10-11,13,16,20,22,25-29,40H,5,8-9,12,14-15H2,1-4,6-7H3/t20-,22-,25-,26+,27-,28+,29-,32+,33+,34-,35+/m0/s1
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InChIKey |
RAKYLPJLLBOHHN-CFTUDFFSSA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | CAAX farnesyltransferase beta (FNTB) | Target Info | Inhibitor | [1] |
KEGG Pathway | Terpenoid backbone biosynthesis | |||
Biosynthesis of antibiotics | ||||
NetPath Pathway | TSH Signaling Pathway | |||
Reactome | Inactivation, recovery and regulation of the phototransduction cascade | |||
WikiPathways | Visual phototransduction |
References | Top | |||
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REF 1 | Modeling of binding modes and inhibition mechanism of some natural ligands of farnesyl transferase using molecular docking. J Med Chem. 2002 Mar 28;45(7):1460-5. |
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