Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D00MZS
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| Former ID |
DNC001336
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| Drug Name |
SK509
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| Synonyms |
Tetrachlorosalicylanilide; 7426/7/5; 2,3,4,5-tetrachloro-6-hydroxy-n-phenylbenzamide; AC1L3YOY; C11274; AC1Q3L4M; SCHEMBL999269; CHEBI:9473; CTK2H9174; DTXSID90225265; 2-Hydroxy-3,4,5,6-tetrachlorobenzanilide; 2,3,4,5-tetrachloro-6-hydroxy-N-phenyl-benzamide
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1], [2] | |
| Structure |
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Download2D MOL |
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| Formula |
C13H7Cl4NO2
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| Canonical SMILES |
C1=CC=C(C=C1)NC(=O)C2=C(C(=C(C(=C2Cl)Cl)Cl)Cl)O
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| InChI |
1S/C13H7Cl4NO2/c14-8-7(12(19)11(17)10(16)9(8)15)13(20)18-6-4-2-1-3-5-6/h1-5,19H,(H,18,20)
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| InChIKey |
BDOBMVIEWHZYDL-UHFFFAOYSA-N
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| CAS Number |
CAS 7426-07-5
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| ChEBI ID |
CHEBI:9473
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Bacterial Sporulation kinase A (Bact kinA) | Target Info | Inhibitor | [1] |
| Coagulation factor Xa (F10) | Target Info | Inhibitor | [2] | |
| KEGG Pathway | Complement and coagulation cascades | |||
| Panther Pathway | Blood coagulation | |||
| Pathwhiz Pathway | Coagulation | |||
| Pathway Interaction Database | Beta2 integrin cell surface interactions | |||
| Reactome | Extrinsic Pathway of Fibrin Clot Formation | |||
| Intrinsic Pathway of Fibrin Clot Formation | ||||
| Common Pathway of Fibrin Clot Formation | ||||
| Gamma-carboxylation of protein precursors | ||||
| Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus | ||||
| Removal of aminoterminal propeptides from gamma-carboxylated proteins | ||||
| WikiPathways | Complement and Coagulation Cascades | |||
| Human Complement System | ||||
| PTM: gamma carboxylation, hypusine formation and arylsulfatase activation | ||||
| Blood Clotting Cascade | ||||
| Formation of Fibrin Clot (Clotting Cascade) | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Histidine kinases as targets for new antimicrobial agents. Bioorg Med Chem. 2002 Apr;10(4):855-67. | |||
| REF 2 | The design and synthesis of noncovalent factor Xa inhibitors. Curr Top Med Chem. 2001 Jun;1(2):137-49. | |||
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