Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D00LYW
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| Former ID |
DIB016287
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| Drug Name |
BW-1003C87
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| Synonyms |
144425-86-5; BW-1003C87; 5-(2,3,5-Trichlorophenyl)pyrimidine-2,4-diamine ethane sulfonate; Ethanesulfonic acid, compd. with 5-(2,3,5-trichlorophenyl)-2,4-pyrimidinediamine (1:1); BW 1003C87; ACMC-20n3z2; AC1L31BW; SCHEMBL15914195; CTK0H6679; DTXSID70162705; AKOS030595718; ethanesulfonic acid
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| Drug Type |
Small molecular drug
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| Indication | Cerebrovascular ischaemia [ICD-11: 8B1Z; ICD-10: I67.8; ICD-9: 434.91] | Terminated | [1] | |
| Company |
Burroughs Wellcome Inc
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| Structure |
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Download2D MOL |
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| Formula |
C12H13Cl3N4O3S
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| Canonical SMILES |
CCS(=O)(=O)O.C1=C(C=C(C(=C1C2=CN=C(N=C2N)N)Cl)Cl)Cl
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| InChI |
1S/C10H7Cl3N4.C2H6O3S/c11-4-1-5(8(13)7(12)2-4)6-3-16-10(15)17-9(6)14;1-2-6(3,4)5/h1-3H,(H4,14,15,16,17);2H2,1H3,(H,3,4,5)
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| InChIKey |
NVKJAOGJEDODFZ-UHFFFAOYSA-N
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| CAS Number |
CAS 144425-86-5
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Sodium channel unspecific (NaC) | Target Info | Modulator | [2] |
| KEGG Pathway | Dopaminergic synapse | |||
| Reactome | Interaction between L1 and Ankyrins | |||
| References | Top | |||
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| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800002740) | |||
| REF 2 | The pyrimidine-derivative, BW1003C87, protects CA1 and striatal neurons following transient severe forebrain ischaemia in rats. A microdialysis and histological study. Neuroscience. 1993 Sep;56(1):93-9. | |||
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