Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D00JNT
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| Former ID |
DIB012434
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| Drug Name |
HCV-086
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| Synonyms |
VP-18344
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|
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| Drug Type |
Small molecular drug
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| Indication | Hepatitis virus infection [ICD-11: 1E50-1E51; ICD-9: 573.3] | Discontinued in Phase 1 | [1] | |
| Company |
ViroPharma; ViroPharma Inc
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| Structure |
 |
Download2D MOL |
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| Formula |
C20H21FN2O5S
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| Canonical SMILES |
CC(C)OC1=C(C=C2C(=C1)C(=C(O2)C3=CC=C(C=C3)F)C(=O)NC)NS(=O)(=O)C
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| InChI |
1S/C20H21FN2O5S/c1-11(2)27-17-9-14-16(10-15(17)23-29(4,25)26)28-19(18(14)20(24)22-3)12-5-7-13(21)8-6-12/h5-11,23H,1-4H3,(H,22,24)
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| InChIKey |
VBRUONUESYTIDA-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Hepatitis C virus RNA-directed RNA polymerase (HCV NS5B) | Target Info | Inhibitor | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800020428) | |||
| REF 2 | Challenges and successes in developing new therapies for hepatitis C. Nature. 2005 Aug 18;436(7053):953-60. | |||
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