Drug Information
Drug General Information | Top | |||
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Drug ID |
D00HQJ
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Drug Name |
PMID25522065-Compound-27
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Drug Type |
Small molecular drug
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Structure |
Download2D MOL |
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Formula |
C23H23F2N7O2
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Canonical SMILES |
COC1=NC2=CC(=C(C=C2N=C1NC(=O)NC3CCN(CC3)CC4=CC5=C(C=C4)C=NN5)F)F
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InChI |
1S/C23H23F2N7O2/c1-34-22-21(28-19-9-16(24)17(25)10-20(19)29-22)30-23(33)27-15-4-6-32(7-5-15)12-13-2-3-14-11-26-31-18(14)8-13/h2-3,8-11,15H,4-7,12H2,1H3,(H,26,31)(H2,27,28,30,33)
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InChIKey |
XSQADOWIAZCVIY-UHFFFAOYSA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Melanin-concentrating hormone receptor 1 (MCHR1) | Target Info | Antagonist | [1] |
Target's Patent Info | Melanin-concentrating hormone receptor 1 (MCHR1) | Target's Patent Info | [1] | |
KEGG Pathway | Neuroactive ligand-receptor interaction | |||
Reactome | Peptide ligand-binding receptors | |||
G alpha (q) signalling events | ||||
G alpha (i) signalling events | ||||
WikiPathways | GPCRs, Class A Rhodopsin-like | |||
Gastrin-CREB signalling pathway via PKC and MAPK | ||||
GPCR ligand binding | ||||
GPCR downstream signaling |
References | Top | |||
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REF 1 | Novel MCH1 receptor antagonists: a patent review.Expert Opin Ther Pat. 2015 Feb;25(2):193-207. |
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