Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D00FPG
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| Former ID |
DNC006464
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| Drug Name |
1-methyl-1H-indole-3-carboxamide
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| Synonyms |
1-methyl-1H-indole-3-carboxamide; 118959-44-7; 1H-Indole-3-carboxamide, 1-methyl-; 1-methylindole-3-carboxamide; CHEMBL382602; AC1LGL0W; ACMC-20mo37; MLS001049055; SCHEMBL2174829; CTK0F9691; DTXSID00356397; MolPort-002-560-820; UHQHFXKJFJHBAE-UHFFFAOYSA-N; HMS2271M13; ZINC341025; BDBM50427552; STK721948; AKOS009024585; MCULE-8790085472; AS-9399; SMR000386893; AJ-19941; KB-219182; FT-0721669
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C10H10N2O
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| Canonical SMILES |
CN1C=C(C2=CC=CC=C21)C(=O)N
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| InChI |
1S/C10H10N2O/c1-12-6-8(10(11)13)7-4-2-3-5-9(7)12/h2-6H,1H3,(H2,11,13)
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| InChIKey |
UHQHFXKJFJHBAE-UHFFFAOYSA-N
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| CAS Number |
CAS 118959-44-7
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Inosine-5'-monophosphate dehydrogenase 2 (IMPDH2) | Target Info | Inhibitor | [1] |
| BioCyc | Purine nucleotides degradation | |||
| Urate biosynthesis/inosine 5'-phosphate degradation | ||||
| Guanosine nucleotides de novo biosynthesis | ||||
| Superpathway of purine nucleotide salvage | ||||
| Purine nucleotides de novo biosynthesis | ||||
| Guanosine ribonucleotides de novo biosynthesis | ||||
| KEGG Pathway | Purine metabolism | |||
| Drug metabolism - other enzymes | ||||
| Metabolic pathways | ||||
| Panther Pathway | De novo purine biosynthesis | |||
| Reactome | Purine ribonucleoside monophosphate biosynthesis | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Low molecular weight indole fragments as IMPDH inhibitors. Bioorg Med Chem Lett. 2006 May 1;16(9):2535-8. | |||
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