Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D00ESG
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| Former ID |
DNC012075
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| Drug Name |
4-Pyridin-2-yl-piperazine-1-carboxylic acid amide
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| Synonyms |
CHEMBL296963; SCHEMBL1270156; CTK7D3440; BDBM50224176; AKOS000158821; 4-(2-pyridyl)piperazine-1-carboxamide
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C10H14N4O
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| Canonical SMILES |
C1CN(CCN1C2=CC=CC=N2)C(=O)N
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| InChI |
1S/C10H14N4O/c11-10(15)14-7-5-13(6-8-14)9-3-1-2-4-12-9/h1-4H,5-8H2,(H2,11,15)
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| InChIKey |
XYIDWLYTWKIZQC-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Transient receptor potential cation channel V1 (TRPV1) | Target Info | Inhibitor | [1] |
| Transient receptor potential cation channel V4 (TRPV4) | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Inflammatory mediator regulation of TRP channels | ||||
| NetPath Pathway | IL2 Signaling Pathway | |||
| Pathway Interaction Database | Trk receptor signaling mediated by the MAPK pathway | |||
| Trk receptor signaling mediated by PI3K and PLC-gamma | ||||
| Reactome | TRP channels | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | N-4-methansulfonamidobenzyl-N'-2-substituted-4-tert-butyl-benzyl thioureas as potent vanilloid receptor antagonistic ligands. Bioorg Med Chem Lett. 2004 Apr 5;14(7):1693-6. | |||
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