Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D00DFP
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| Drug Name |
KBP-5074
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| Indication | Hypertension [ICD-11: BA00-BA04; ICD-9: 401] | Phase 1/2 | [1] | |
| Company |
KBP Biosciences Princeton, NJ
|
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| Structure |
 |
Download2D MOL |
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| Formula |
C28H30ClN5O2
|
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| Canonical SMILES |
C1CCC(C1)C2C3CCC4=C(C3=NN2C5=CC(=C(C=C5)C#N)Cl)C=CC(=N4)C(=O)N6CCC(CC6)O
|
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| InChI |
1S/C28H30ClN5O2/c29-23-15-19(6-5-18(23)16-30)34-27(17-3-1-2-4-17)22-8-9-24-21(26(22)32-34)7-10-25(31-24)28(36)33-13-11-20(35)12-14-33/h5-7,10,15,17,20,22,27,35H,1-4,8-9,11-14H2/t22-,27+/m1/s1
|
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| InChIKey |
UXHQLGLGLZKHTC-AMGIVPHBSA-N
|
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Mineralocorticoid receptor (MR) | Target Info | Antagonist | [1] |
| KEGG Pathway | Aldosterone-regulated sodium reabsorption | |||
| Pathwhiz Pathway | Kidney Function | |||
| WikiPathways | ACE Inhibitor Pathway | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA) | |||
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