Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D00CRQ
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| Drug Name |
Phenylate derivative 1
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| Synonyms |
PMID30107136-Compound-Example21
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| Drug Type |
Small molecule immunotherapy
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| Indication | Hepatitis [ICD-11: DB97.Z] | Patented | [1] | |
| Human immunodeficiency virus infection [ICD-11: 1C62; ICD-9: 42] | Patented | [1] | ||
| Infectious disease [ICD-11: 1A00-CA43.1; ICD-10: A00-B99; ICD-9: 001-139] | Patented | [1] | ||
| Solid tumour/cancer [ICD-11: 2A00-2F9Z; ICD-10: C76-C80; ICD-9: 140-229] | Patented | [1] | ||
| Company |
INST OF MATERIA MEDICA CHINESE ACADEMY OF MEDICAL SCIENCES [CN]
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| Structure |
 |
Download2D MOL |
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| Formula |
C28H29BrClNO5
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| Canonical SMILES |
CC(=CCOC1=CC(=C(C=C1CNC(CO)C(=O)O)Cl)OCC2=C(C(=CC=C2)C3=CC=CC=C3)Br)C
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| InChI |
1S/C28H29BrClNO5/c1-18(2)11-12-35-25-14-26(23(30)13-21(25)15-31-24(16-32)28(33)34)36-17-20-9-6-10-22(27(20)29)19-7-4-3-5-8-19/h3-11,13-14,24,31-32H,12,15-17H2,1-2H3,(H,33,34)
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| InChIKey |
HXFYELRCMXNMTR-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | PD-1-PD-L1 interaction (PD-1/PD-L1 PPI) | Target Info | Inhibitor | [1] |
| Target's Patent Info | PD-1-PD-L1 interaction (PD-1/PD-L1 PPI) | Target's Patent Info | [1] | |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | A patent review on PD-1/PD-L1 antagonists: small molecules, peptides, and macrocycles (2015-2018).Expert Opin Ther Pat. 2018 Sep;28(9):665-678. | |||
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