Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D00BQR
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| Drug Name |
PMID28870136-Compound-57
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| Drug Type |
Small molecular drug
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| Company |
ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC
|
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| Structure |
 |
Download2D MOL |
||
| Formula |
C11H12ClFN4O3
|
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| Canonical SMILES |
C1=CN(C2=NC(=NC(=C21)N)Cl)C3C(C(C(O3)CO)O)F
|
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| InChI |
1S/C11H12ClFN4O3/c12-11-15-8(14)4-1-2-17(9(4)16-11)10-6(13)7(19)5(3-18)20-10/h1-2,5-7,10,18-19H,3H2,(H2,14,15,16)/t5-,6+,7-,10-/m1/s1
|
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| InChIKey |
VLXMLGCQJSJFSY-JTGULSINSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Ecto-5'-nucleotidase (CD73) | Target Info | Inhibitor | [1] |
| Target's Patent Info | Ecto-5'-nucleotidase (CD73) | Target's Patent Info | [1] | |
| BioCyc | Purine nucleotides degradation | |||
| Urate biosynthesis/inosine 5'-phosphate degradation | ||||
| Adenosine nucleotides degradation | ||||
| KEGG Pathway | Purine metabolism | |||
| Pyrimidine metabolism | ||||
| Nicotinate and nicotinamide metabolism | ||||
| Metabolic pathways | ||||
| Panther Pathway | Purine metabolism | |||
| Pyrimidine Metabolism | ||||
| Pathway Interaction Database | HIF-1-alpha transcription factor network | |||
| Reactome | Purine catabolism | |||
| WikiPathways | Differentiation Pathway | |||
| miR-targeted genes in muscle cell - TarBase | ||||
| miR-targeted genes in lymphocytes - TarBase | ||||
| miR-targeted genes in epithelium - TarBase | ||||
| Metabolism of nucleotides | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Ectonucleotidase inhibitors: a patent review (2011-2016).Expert Opin Ther Pat. 2017 Dec;27(12):1291-1304. | |||
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