Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0W7JZ
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| Former ID |
DNCL002107
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| Drug Name |
Tivozanib
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| Synonyms |
ASP4130/AV-951
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| Drug Type |
Small molecular drug
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| Indication | Renal cell carcinoma [ICD-11: 2C90; ICD-10: C64; ICD-9: 189] | Approved | [1] | |
| Company |
Astellas Pharma US; AVEO Pharmaceuticals
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| Structure |
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Download2D MOL |
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| Formula |
C22H19ClN4O5
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| Canonical SMILES |
CC1=CC(=NO1)NC(=O)NC2=C(C=C(C=C2)OC3=C4C=C(C(=CC4=NC=C3)OC)OC)Cl
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| InChI |
1S/C22H19ClN4O5/c1-12-8-21(27-32-12)26-22(28)25-16-5-4-13(9-15(16)23)31-18-6-7-24-17-11-20(30-3)19(29-2)10-14(17)18/h4-11H,1-3H3,(H2,25,26,27,28)
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| InChIKey |
SPMVMDHWKHCIDT-UHFFFAOYSA-N
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| CAS Number |
CAS 475108-18-0
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| PubChem Compound ID | ||||
| PubChem Substance ID |
14882223, 24192058, 45983488, 78829796, 99302829, 99437027, 99453618, 123051118, 123087413, 123110210, 124490423, 124757081, 124955473, 125163885, 125570998, 126659904, 126731226, 131480730, 135261059, 135685196, 135685197, 135685214, 135685972, 135685973, 135685994, 135685995, 136340121, 136367363, 136920274, 137262648, 139498427, 143499542, 144115647, 144187404, 152234928, 152258283, 152344393, 160647122, 162011363, 162037498, 162201687, 163685747, 170484711, 170496628, 170502198, 172914257, 174560995, 175607447, 177748705, 178102679
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| ChEBI ID |
CHEBI:91327
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| References | Top | |||
|---|---|---|---|---|
| REF 1 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health Human Services | |||
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