Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0QQ1J
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| Former ID |
DNC011355
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| Drug Name |
BITHIONOL
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| Synonyms |
bithionol; 97-18-7; Actamer; Bithin; 2,2'-Thiobis(4,6-dichlorophenol); Lorothidol; Bitionol; Bithionol sulfide; Bisoxyphen; Bidiphen; Lorothiodol; Bitin; Nobacter; Bithionolate; Neopellis; Vancide BL; Usaf B-22; Bithional; Bithionolum; 2-Hydroxy-3,5-dichlorophenyl sulfide; TKhsd; Bis(2-hydroxy-3,5-dichlorophenyl) sulfide; Bis(3,5-dichloro-2-hydroxyphenyl) sulfide; 2,2'-sulfanediylbis(4,6-dichlorophenol); Caswell No. 852; Bitionol [INN-Spanish]; XL 7; Bithionolum [INN-Latin]; 2,2'-Dihydroxy-3,3',5,5'-tetrachlorodiphenyl sulfide
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| Drug Type |
Small molecular drug
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| Indication | Trematode infection [ICD-11: 1F8Y] | Withdrawn from market | [1], [2] | |
| Structure |
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Download2D MOL |
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| Formula |
C12H6Cl4O2S
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| Canonical SMILES |
C1=C(C=C(C(=C1SC2=C(C(=CC(=C2)Cl)Cl)O)O)Cl)Cl
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| InChI |
1S/C12H6Cl4O2S/c13-5-1-7(15)11(17)9(3-5)19-10-4-6(14)2-8(16)12(10)18/h1-4,17-18H
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| InChIKey |
JFIOVJDNOJYLKP-UHFFFAOYSA-N
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| CAS Number |
CAS 97-18-7
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| PubChem Compound ID | ||||
| PubChem Substance ID |
10168, 75233, 100332, 603045, 855531, 4908298, 7847867, 8149224, 8151613, 10538866, 11335814, 11361053, 11362922, 11365484, 11368046, 11371518, 11373833, 11376208, 11462025, 11483862, 11487929, 11490135, 11492072, 11493902, 11533319, 12054579, 15472383, 17389712, 24900609, 26751444, 29221571, 46508019, 47365181, 47440246, 47662279, 47959736, 48184990, 48414531, 48422207, 48424455, 49856124, 50100878, 56313666, 56404185, 56459051, 57321306, 57654715, 74382877, 78335568, 87576694
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| ChEBI ID |
CHEBI:3131
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| SuperDrug ATC ID |
D10AB01; P02BX01
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| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2338). | |||
| REF 2 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015 | |||
| REF 3 | In silico identification and biochemical evaluation of novel inhibitors of NRH:quinone oxidoreductase 2 (NQO2). Bioorg Med Chem Lett. 2010 Dec 15;20(24):7331-6. | |||
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