Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0KG9M
|
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| Drug Name |
PMID27998201-Compound-22
|
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| Drug Type |
Small molecular drug
|
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| Indication | Alzheimer disease [ICD-11: 8A20; ICD-10: G30, G30.9; ICD-9: 331] | Patented | [1] | |
| Neurodegenerative disorder [ICD-11: 8A20-8A23] | Patented | [1] | ||
| Osteoarthritis [ICD-11: FA00-FA05; ICD-9: 715] | Patented | [1] | ||
| Pancreatitis [ICD-11: DC31-DC34] | Patented | [1] | ||
| Structure |
 |
Download2D MOL |
||
| Formula |
C9H6N2O3
|
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| Canonical SMILES |
C1=CC2=C(C=CC(=C2N=C1)O)[N+](=O)[O-]
|
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| InChI |
1S/C9H6N2O3/c12-8-4-3-7(11(13)14)6-2-1-5-10-9(6)8/h1-5,12H
|
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| InChIKey |
RJIWZDNTCBHXAL-UHFFFAOYSA-N
|
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| CAS Number |
CAS 4008-48-4
|
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| PubChem Compound ID | ||||
| ChEBI ID |
CHEBI:67121
|
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Cathepsin B (CTSB) | Target Info | Inhibitor | [1] |
| Target's Patent Info | Cathepsin B (CTSB) | Target's Patent Info | [1] | |
| KEGG Pathway | Lysosome | |||
| Antigen processing and presentation | ||||
| NetPath Pathway | TCR Signaling Pathway | |||
| IL2 Signaling Pathway | ||||
| Reactome | Collagen degradation | |||
| Trafficking and processing of endosomal TLR | ||||
| Assembly of collagen fibrils and other multimeric structures | ||||
| MHC class II antigen presentation | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Cathepsin B and L inhibitors: a patent review (2010 - present).Expert Opin Ther Pat. 2017 Jun;27(6):643-656. | |||
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