Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0K8KX
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| Former ID |
DAP001419
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| Drug Name |
Quercetin
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| Synonyms |
Kvercetin; Meletin; QUE; Quercetine; Quercetol; Quercitin; Quertin; Quertine; Sophoretin; Xanthaurine; Flavin meletin; Kvercetin [Czech]; Quercetin content; Quercetin dihydrate; CI Natural Yellow 10; Cyanidelonon 1522; KUC104418N; KUC107684N; MixCom3_000183; Natural Yellow 10; P0042; Q 0125; TNP00070; TNP00089; LIM-5662; LNS-5662; C.I . natural yellow 10; C.I. 75670; C.I. Natural Yellow 10; C.I. Natural red 1; CU-01000012502-3; KSC-10-126; KSC-23-76; T-Gelb bzw. grun 1; C.I. Natural yellow 10 & 13; 2-(3,4-Dihydroxy-phenyl)-3,5,7-trihydroxy-chromen-4-one; 2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxy-4H-1-benzopyran-4-one; 2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxy-4H-1-benzopyran-4-one dihydrate; 2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxy-4H-chromen-4-one; 2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxychromen-4-one; 3',4',5,7-Tetrahydroxyflavan-3-ol; 3',4',5,7-tetrahydroxyflavon-3-ol; 3,3',4',5,7-Pentahydroxyflavone dihydrate; 3,5,7,3',4'-Pentahydroxyflavone; 3,5,7-Trihydroxy-2-(3,4-dihydroxyphenyl)-4H-chromen-4-on; 3,5,7-trihydroxy-2-(3,4-dihydroxyphenyl)-4H-chromen-4-one
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| Drug Type |
Small molecular drug
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| Indication | Obesity [ICD-11: 5B81; ICD-10: E66; ICD-9: 278] | Approved | [1], [2] | |
| Therapeutic Class |
Hypoglycemic Agents
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| Structure |
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Download2D MOL |
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| Formula |
C15H10O7
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| Canonical SMILES |
C1=CC(=C(C=C1C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O)O)O
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| InChI |
1S/C15H10O7/c16-7-4-10(19)12-11(5-7)22-15(14(21)13(12)20)6-1-2-8(17)9(18)3-6/h1-5,16-19,21H
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| InChIKey |
REFJWTPEDVJJIY-UHFFFAOYSA-N
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| CAS Number |
CAS 117-39-5
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| PubChem Compound ID | ||||
| PubChem Substance ID |
3679, 74741, 596331, 820896, 821326, 841197, 3157247, 5183365, 7636346, 7884117, 7890165, 8137945, 8145679, 8149624, 8616230, 10318962, 10318963, 10589526, 11108251, 11111704, 11111705, 11111706, 11113933, 11120249, 11120737, 11121225, 11121719, 11122199, 11335660, 11360899, 11362822, 11362998, 11365384, 11365560, 11367946, 11368122, 11370875, 11370876, 11371563, 11373547, 11374432, 11376108, 11376284, 11387263, 11401319, 11446388, 11455076, 11455328, 11461871, 11466535
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| ChEBI ID |
CHEBI:16243
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| SuperDrug ATC ID |
C05CA01
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| SuperDrug CAS ID |
cas=000153184
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Acetyl-CoA:lyso-PAF acetyltransferase (PCAT) | Target Info | Inhibitor | [2], [3] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5346). | |||
| REF 2 | Modulation by flavonoids of PAF and related phospholipids in endothelial cells during oxidative stress. J Lipid Res. 2003 Feb;44(2):380-7. | |||
| REF 3 | Inhibition of lysoPAF acetyltransferase activity by flavonoids. Inflamm Res. 1996 Nov;45(11):546-9. | |||
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