Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0K7WQ
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| Drug Name |
GS-441524
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| Synonyms |
EVO984; EVO-984; EVO 984; GS 441524; GS441524
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| Drug Type |
Small molecular drug
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| Indication | Coronavirus Disease 2019 (COVID-19) [ICD-11: 1D6Y] | Investigative | [1] | |
| Therapeutic Class |
Antiviral Agents
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| Structure |
 |
Download2D MOL |
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| Formula |
C12H13N5O4
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| Canonical SMILES |
C1=C2C(=NC=NN2C(=C1)C3(C(C(C(O3)CO)O)O)C#N)N
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| InChI |
1S/C12H13N5O4/c13-4-12(10(20)9(19)7(3-18)21-12)8-2-1-6-11(14)15-5-16-17(6)8/h1-2,5,7,9-10,18-20H,3H2,(H2,14,15,16)/t7-,9-,10-,12+/m1/s1
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| InChIKey |
BRDWIEOJOWJCLU-LTGWCKQJSA-N
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| CAS Number |
CAS 1191237-69-0
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| PubChem Compound ID | ||||
| ChEBI ID |
CHEBI:147281
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | COVID-19 replicase polyprotein 1ab (pp1ab) | Target Info | Inhibitor | [1] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Current knowledge about the antivirals remdesivir (GS-5734) and GS-441524 as therapeutic options for coronaviruses. One Health. 2020 Mar 27;9:100128. | |||
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