Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0H4DR
|
|||
| Former ID |
DIB011801
|
|||
| Drug Name |
BMS-852927
|
|||
| Indication | Arteriosclerosis [ICD-11: BD40; ICD-10: I70] | Phase 1 | [1] | |
| Company |
Bristol-myers squibb
|
|||
| Structure |
 |
Download2D MOL |
||
| Formula |
C29H28Cl2F2N2O4S
|
|||
| Canonical SMILES |
CC(C)(C1=CN(C(=N1)C(C)(C)C2=C(C=CC=C2Cl)Cl)C3=C(C=C(C=C3)C4=CC(=C(C(=C4)S(=O)(=O)C)CO)F)F)O
|
|||
| InChI |
1S/C29H28Cl2F2N2O4S/c1-28(2,26-19(30)7-6-8-20(26)31)27-34-25(29(3,4)37)14-35(27)23-10-9-16(11-22(23)33)17-12-21(32)18(15-36)24(13-17)40(5,38)39/h6-14,36-37H,15H2,1-5H3
|
|||
| InChIKey |
HNAJDMYOTDNOBK-UHFFFAOYSA-N
|
|||
| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Oxysterols receptor LXR (NR1H) | Target Info | Modulator | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | ClinicalTrials.gov (NCT01651273) A Safety Study of BMS-852927 in Subjects With Hypercholesterolemia. U.S. National Institutes of Health. | |||
| REF 2 | Liver X receptors in lipid metabolism: opportunities for drug discovery. Nat Rev Drug Discov. 2014 Jun;13(6):433-44. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.