Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0G5UB
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| Former ID |
DAP000321
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| Drug Name |
Amlexanox
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| Synonyms |
ANW; Amlenanox; Amlexanoxo; Amlexanoxum; Amoxanox; Aphthasol; Aptheal; Apthera; Elics; OraDisc; OraRinse; Solfa; Amlexanoxo [Spanish]; Amlexanoxum [Latin]; GlaxoSmithKline brand of amlexanox; OraDisc A; AA 673; CHX 3673; AA-673; Aphthasol (TN); CHX-3673; Solfa (TN); Amlexanox [USAN:INN:JAN]; Amlexanox (JAN/USAN/INN); 2-Amino-7-isopropyl-5-oxo-5H-(1)benzopyrano(2,3-b)pyridine-3-carboxylic acid; 2-amino-5-oxo-7-(propan-2-yl)-5H-chromeno[2,3-b]pyridine-3-carboxylic acid; 2-amino-5-oxo-7-propan-2-ylchromeno[2,3-b]pyridine-3-carboxylic acid; 2-amino-7-(1-methylethyl)-5-oxo-5H-chromeno[2,3-b]pyridine-3-carboxylic acid; 2-amino-7-isopropyl-5-oxo-5H-(1)benzopyrano(2,3b)pyridine-3-carboxylic acid
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| Drug Type |
Small molecular drug
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| Indication | Respiratory tract inflammation [ICD-11: CA07; ICD-10: J00-J99] | Approved | [1], [2], [3] | |
| Therapeutic Class |
Antiulcer Agents
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| Company |
Access Pharmaceuticals
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| Structure |
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Download2D MOL |
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| Formula |
C16H14N2O4
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| Canonical SMILES |
CC(C)C1=CC2=C(C=C1)OC3=NC(=C(C=C3C2=O)C(=O)O)N
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| InChI |
1S/C16H14N2O4/c1-7(2)8-3-4-12-9(5-8)13(19)10-6-11(16(20)21)14(17)18-15(10)22-12/h3-7H,1-2H3,(H2,17,18)(H,20,21)
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| InChIKey |
SGRYPYWGNKJSDL-UHFFFAOYSA-N
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| CAS Number |
CAS 68302-57-8
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| PubChem Compound ID | ||||
| PubChem Substance ID |
4436378, 7848890, 8151469, 12012752, 14800376, 26719859, 29221340, 46386726, 46504508, 48415555, 49681589, 49889816, 50112726, 51031833, 53787694, 57321179, 85175357, 85209734, 87322640, 89449260, 92308343, 92712117, 93166867, 103303757, 104299784, 118314594, 124658947, 124801314, 124893315, 125356092, 126630208, 126656917, 126665953, 129233636, 131323546, 134337633, 135009198, 135723231, 136376454, 137006051, 139650939, 143104826, 144206029, 152039917, 160812411, 160871486, 160964361, 162022097, 162177589, 163089314
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| ChEBI ID |
CHEBI:31205
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| ADReCS Drug ID | BADD_D00120 | |||
| SuperDrug ATC ID |
A01AD07; R03DX01
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| SuperDrug CAS ID |
cas=068302578
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| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7113). | |||
| REF 2 | An inhibitor of the protein kinases TBK1 and IKK- improves obesity-related metabolic dysfunctions in mice. Nat Med. 2013 Mar;19(3):313-21. | |||
| REF 3 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015 | |||
| REF 4 | Hsp90 is a direct target of the anti-allergic drugs disodium cromoglycate and amlexanox. Biochem J. 2003 Sep 1;374(Pt 2):433-41. | |||
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