Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0DJ4A
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| Former ID |
DIB008052
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| Drug Name |
Preverex
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| Synonyms |
Biostent; Phomin; Cytochalasin B; Cytochalasin B containing stent
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| Drug Type |
Small molecular drug
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| Indication | Artery stenosis [ICD-11: BD52; ICD-10: I51.89] | Phase 2 | [1], [2] | |
| Company |
Poniard Pharmaceuticals Inc
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| Structure |
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Download2D MOL |
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| Formula |
C29H37NO5
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| Canonical SMILES |
CC1CCCC(C=CC(=O)OC23C(C=CC1)C(C(=C)C(C2C(NC3=O)CC4=CC=CC=C4)C)O)O
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| InChI |
1S/C29H37NO5/c1-18-9-7-13-22(31)15-16-25(32)35-29-23(14-8-10-18)27(33)20(3)19(2)26(29)24(30-28(29)34)17-21-11-5-4-6-12-21/h4-6,8,11-12,14-16,18-19,22-24,26-27,31,33H,3,7,9-10,13,17H2,1-2H3,(H,30,34)/b14-8+,16-15+/t18-,19-,22-,23+,24+,26+,27-,29-/m1/s1
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| InChIKey |
GBOGMAARMMDZGR-TYHYBEHESA-N
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| CAS Number |
CAS 14930-96-2
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| PubChem Compound ID | ||||
| PubChem Substance ID |
407385, 7979954, 11056405, 11532949, 14810039, 14932446, 24858145, 24892890, 26680892, 26756820, 26756821, 26758528, 39340980, 47424981, 47424982, 48019681, 48394635, 50941572, 56422442, 57359416, 74380554, 92310016, 99300928, 99302448, 103567159, 119503397, 124637606, 135626420, 162187687, 163688309, 178101998, 198962391, 223441394, 252347741, 252455740, 252818423
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| ChEBI ID |
CHEBI:23527
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Actin polymerization (Actin poly) | Target Info | Modulator | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5334). | |||
| REF 2 | Chronic hypoxia differentially up-regulates protein kinase C-mediated ovine uterine arterial contraction via actin polymerization signaling in pregnancy. Biol Reprod. 2012 Dec 21;87(6):142. | |||
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