Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0D0ZD
|
|||
| Former ID |
DAP000712
|
|||
| Drug Name |
Miglitol
|
|||
| Synonyms |
Diastabol; Glyset; Plumarol; Seibule; Glyset (TN); SK-983; Bay-m-1099; Miglitol (JAN/USAN/INN); (2R,3R,4R,5S)-1-(2-hydroxyethyl)-2-(hydroxymethyl)piperidine-3,4,5-triol
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Diabetic complication [ICD-11: 5A2Y; ICD-9: 253.5, 588.1] | Approved | [1], [2] | |
| Therapeutic Class |
Hypoglycemic Agents
|
|||
| Structure |
 |
Download2D MOL |
||
| Formula |
C8H17NO5
|
|||
| Canonical SMILES |
C1C(C(C(C(N1CCO)CO)O)O)O
|
|||
| InChI |
1S/C8H17NO5/c10-2-1-9-3-6(12)8(14)7(13)5(9)4-11/h5-8,10-14H,1-4H2/t5-,6+,7-,8-/m1/s1
|
|||
| InChIKey |
IBAQFPQHRJAVAV-ULAWRXDQSA-N
|
|||
| CAS Number |
CAS 72432-03-2
|
|||
| PubChem Compound ID | ||||
| PubChem Substance ID |
9910, 7847691, 10298793, 12013518, 14773217, 26719889, 36885182, 46386758, 46482884, 46504492, 48416282, 49681630, 57403633, 76272887, 81092900, 87457737, 92308295, 93166890, 103582154, 104099012, 104625177, 124658920, 128142046, 131324823, 134338000, 135010524, 135692539, 135710047, 135727713, 136897490, 137005784, 142774177, 143493315, 143500463, 144204989, 152109108, 152164711, 152235777, 152250007, 160871160, 160963837, 162178849, 163136017, 165699402, 170465326, 172080293, 174530493, 175266934, 178101544, 179116789
|
|||
| ChEBI ID |
CHEBI:6935
|
|||
| ADReCS Drug ID | BADD_D01464 | |||
| SuperDrug ATC ID |
A10BF02
|
|||
| SuperDrug CAS ID |
cas=072432032
|
|||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Intestinal maltase-glucoamylase (MGAM) | Target Info | Inhibitor | [3] |
| KEGG Pathway | Galactose metabolism | |||
| Starch and sucrose metabolism | ||||
| Metabolic pathways | ||||
| Carbohydrate digestion and absorption | ||||
| Pathwhiz Pathway | Starch and Sucrose Metabolism | |||
| WikiPathways | Metabolism of carbohydrates | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4842). | |||
| REF 2 | Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77. | |||
| REF 3 | Drug therapy of postprandial hyperglycaemia. Drugs. 1999 Jan;57(1):19-29. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.