Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0B2WZ
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| Former ID |
DIB019693
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| Drug Name |
daminozide
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| Synonyms |
DMASA; SADH; B 995; Alar; Kylar; B-NINE
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL
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| Formula |
C6H12N2O3
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| Canonical SMILES |
CN(C)NC(=O)CCC(=O)O
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| InChI |
1S/C6H12N2O3/c1-8(2)7-5(9)3-4-6(10)11/h3-4H2,1-2H3,(H,7,9)(H,10,11)
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| InChIKey |
NOQGZXFMHARMLW-UHFFFAOYSA-N
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| CAS Number |
CAS 1596-84-5
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| PubChem Compound ID | ||||
| PubChem Substance ID |
13179, 3137309, 5573954, 8161512, 10509559, 15091185, 17389951, 24868896, 24899214, 26534314, 26752960, 29283298, 48413511, 48421286, 48423218, 48425635, 48425828, 49855073, 50105565, 57244226, 57328952, 57650350, 75240839, 85089598, 89777556, 96021394, 104336863, 118307174, 124442833, 124653241, 124890701, 124890702, 125501298, 126691405, 127286122, 127286123, 127286124, 127286125, 127286126, 127286127, 127286128, 127286129, 127286130, 127286131, 127286132, 127286133, 127286134, 127286135, 127286136, 127286137
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| ChEBI ID |
CHEBI:4312
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Histone lysine demethylase PHF8 (PHF8) | Target Info | Inhibitor | [1] |
| Lysine-specific demethylase 2A (KDM2A) | Target Info | Inhibitor | [1] | |
| Lysine-specific demethylase 7A (KDM7A) | Target Info | Inhibitor | [1] | |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Plant growth regulator daminozide is a selective inhibitor of human KDM2/7 histone demethylases. J Med Chem. 2012 Jul 26;55(14):6639-43. | |||
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