Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D08YZM
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| Former ID |
DNC010255
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| Drug Name |
4-(piperazin-1-yl)-7H-pyrrolo[2,3-d]pyrimidine
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| Synonyms |
252722-52-4; 4-(Piperazin-1-yl)-1H-pyrrolo[2,3-d]pyrimidine; 4-(piperazin-1-yl)-7H-pyrrolo[2,3-d]pyrimidine; 4-(1-Piperazinyl)-1H-pyrrolo[2,3-d]pyrimidine; CHEMBL595554; 1-{7H-pyrrolo[2,3-d]pyrimidin-4-yl}piperazine; 6J9; SCHEMBL2251760; DTXSID20592472; MolPort-028-913-269; BDBM50304819; AKOS022175220; AKOS016374229; MCULE-3871238079; ACM252722524; NS-02114; DB-067363; AX8159612; KB-186079; AJ-103002
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C10H13N5
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| Canonical SMILES |
C1CN(CCN1)C2=NC=NC3=C2C=CN3
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| InChI |
1S/C10H13N5/c1-2-12-9-8(1)10(14-7-13-9)15-5-3-11-4-6-15/h1-2,7,11H,3-6H2,(H,12,13,14)
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| InChIKey |
LZSXQBNNRGZPES-UHFFFAOYSA-N
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| CAS Number |
CAS 252722-52-4
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | 5-HT 2C receptor (HTR2C) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Calcium signaling pathway | |||
| Neuroactive ligand-receptor interaction | ||||
| Gap junction | ||||
| Serotonergic synapse | ||||
| Inflammatory mediator regulation of TRP channels | ||||
| Panther Pathway | 5HT2 type receptor mediated signaling pathway | |||
| Reactome | Serotonin receptors | |||
| G alpha (q) signalling events | ||||
| WikiPathways | Serotonin Receptor 2 and ELK-SRF/GATA4 signaling | |||
| Monoamine GPCRs | ||||
| GPCRs, Class A Rhodopsin-like | ||||
| Gastrin-CREB signalling pathway via PKC and MAPK | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Design and synthesis of orally-active and selective azaindane 5HT2c agonist for the treatment of obesity. Bioorg Med Chem Lett. 2010 Jan 1;20(1):266-71. | |||
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