Drug Information
Drug General Information | Top | |||
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Drug ID |
D08NKJ
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Former ID |
DNC000709
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Drug Name |
Guanine
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Drug Type |
Small molecular drug
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Structure |
Download2D MOL |
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Formula |
C5H5N5O
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Canonical SMILES |
C1=NC2=C(N1)C(=O)NC(=N2)N
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InChI |
1S/C5H5N5O/c6-5-9-3-2(4(11)10-5)7-1-8-3/h1H,(H4,6,7,8,9,10,11)
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InChIKey |
UYTPUPDQBNUYGX-UHFFFAOYSA-N
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CAS Number |
CAS 73-40-5
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PubChem Compound ID | ||||
PubChem Substance ID |
2779, 3541, 585679, 594396, 618937, 832638, 833698, 836921, 841460, 854934, 854953, 855322, 1433762, 3133367, 4491989, 4963597, 5161786, 6184055, 7004212, 7377195, 7644358, 7888029, 8022280, 8145637, 8150777, 10534208, 11416826, 14891624, 16020045, 16105542, 24277513, 24439126, 24697815, 24697817, 24697819, 24697820, 24697835, 24697922, 24895044, 24895050, 24895274, 25622131, 26683839, 26711837, 26712763, 26713089, 26717511, 26717514, 26750333, 26750346
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ChEBI ID |
CHEBI:16235
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Target and Pathway | Top | |||
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Target(s) | GTP cyclohydrolase-I (GCH1) | Target Info | Inhibitor | [1] |
Pathwhiz Pathway | Pterine Biosynthesis | |||
Reactome | Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation |
References | Top | |||
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REF 1 | GTP cyclohydrolase I feedback regulatory protein-dependent and -independent inhibitors of GTP cyclohydrolase I. Arch Biochem Biophys. 2001 Apr 1;388(1):67-73. |
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