Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D08GSF
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| Former ID |
DAP000995
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| Drug Name |
Proflavine
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| Synonyms |
PRL; Proflavin; Proflavina; Proflavinum; Profura; Progarmed; Isoflav base; Proflavine [INN]; Proflavine hemisulfate; Proflavina [INN-Spanish]; Proflavine Hemi-Sulfate; Proflavinum [INN-Latin]; AE-562/12222295; Acridine-3,6-diamine; 2,8-Diaminoacridine; 2,8-Diaminoacridine (European); 2,8-Diaminoacridinium; 3,6-ACRIDINEDIAMINE; 3,6-Acridinediamine hydrochloride; 3,6-Diamino-acridinium; 3,6-Diaminoacridine; 3,6-Diaminoacridine sulfate; 3,6-Diaminoacridinium; 3,7-Diamino-5-azaanthracene
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| Drug Type |
Small molecular drug
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| Indication | Sepsis [ICD-11: 1G40-1G41; ICD-9: 995.91] | Approved | [1] | |
| Therapeutic Class |
Antiinfective Agents
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| Structure |
 |
Download2D MOL |
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| Formula |
C13H11N3
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| Canonical SMILES |
C1=CC(=CC2=NC3=C(C=CC(=C3)N)C=C21)N
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| InChI |
1S/C13H11N3/c14-10-3-1-8-5-9-2-4-11(15)7-13(9)16-12(8)6-10/h1-7H,14-15H2
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| InChIKey |
WDVSHHCDHLJJJR-UHFFFAOYSA-N
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| CAS Number |
CAS 92-62-6
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| PubChem Compound ID | ||||
| PubChem Substance ID |
13362, 597206, 831294, 6902239, 7890047, 8154696, 10538028, 11409033, 11409157, 11436429, 11446857, 14773275, 16959146, 26703197, 29218003, 29226007, 46391536, 46393030, 46393031, 46505401, 46513046, 49864280, 51075611, 57323951, 57581409, 58017465, 79664590, 85088913, 85088914, 85256541, 87349924, 87691790, 96100151, 103244999, 104313972, 117528939, 117528940, 118081085, 121282165, 124360823, 124513852, 124893244, 125649137, 126678395, 126691684, 129567308, 131732471, 134338265, 134972357, 137005971
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| ChEBI ID |
CHEBI:8452
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Bacterial Deoxyribonucleic acid (Bact DNA) | Target Info | Binder | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Drug information of Proflavine, 2008. eduDrugs. | |||
| REF 2 | Interaction of small molecules with double-stranded RNA: spectroscopic, viscometric, and calorimetric study of hoechst and proflavine binding to PolyCG structures. DNA Cell Biol. 2009 Apr;28(4):209-19. | |||
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