Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D06WJC
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| Former ID |
DNC002608
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| Drug Name |
GC-24
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| Synonyms |
GC 24; N-[2-(dimethylamino)ethyl]-2-methylpropanamide; Propanamide, N-(2-(dimethylamino)ethyl)-2-methyl-; BRN 2350680; 63224-17-9; N-(2-(Dimethylamino)ethyl)-2-methylpropanamide; AC1MIL8W; SCHEMBL2624391; DTXSID70212592; MolPort-008-439-279; ZINC11638438; AKOS009104316; MCULE-5485385679; NE11932; LS-119191; N-(2-dimethylaminoethyl)-2-methylpropanamide; EN300-86303
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| Drug Type |
Small molecular drug
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| Indication | Hyperthyroidism [ICD-11: 5A02; ICD-10: E05; ICD-9: 242] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C24H24O4
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| Canonical SMILES |
CC1=CC(=CC(=C1CC2=CC(=C(C=C2)O)CC3=CC=CC=C3)C)OCC(=O)O
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| InChI |
1S/C24H24O4/c1-16-10-21(28-15-24(26)27)11-17(2)22(16)14-19-8-9-23(25)20(13-19)12-18-6-4-3-5-7-18/h3-11,13,25H,12,14-15H2,1-2H3,(H,26,27)
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| InChIKey |
JYHIGYLGYNCMGI-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Thyroid hormone receptor beta (THRB) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Thyroid hormone signaling pathway | ||||
| Pathway Interaction Database | RXR and RAR heterodimerization with other nuclear receptor | |||
| Reactome | Nuclear Receptor transcription pathway | |||
| WikiPathways | SIDS Susceptibility Pathways | |||
| Hematopoietic Stem Cell Differentiation | ||||
| Nuclear Receptors | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6. | |||
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