Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D04NGS
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| Former ID |
DNC006694
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| Drug Name |
JNJ-7706621
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| Synonyms |
JNJ-7706621; 443797-96-4; JNJ7706621; 4-((5-Amino-1-(2,6-difluorobenzoyl)-1H-1,2,4-triazol-3-yl)amino)benzenesulfonamide; UNII-74GK72DON8; RWJ-387252; 4-[[5-amino-1-(2,6-difluorobenzoyl)-1,2,4-triazol-3-yl]amino]benzenesulfonamide; CHEMBL191003; 74GK72DON8; 4-[[5-Amino-1-(2,6-difluorobenzoyl)-1H-1,2,4-triazol-3-yl]amino]benzenesulfonamide; JNJ 7706621; 4-(5-amino-1-(2,6-difluorobenzoyl)-1H-1,2,4-triazol-3-ylamino)benzenesulfonamide
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C15H12F2N6O3S
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| Canonical SMILES |
C1=CC(=C(C(=C1)F)C(=O)N2C(=NC(=N2)NC3=CC=C(C=C3)S(=O)(=O)N)N)F
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| InChI |
1S/C15H12F2N6O3S/c16-10-2-1-3-11(17)12(10)13(24)23-14(18)21-15(22-23)20-8-4-6-9(7-5-8)27(19,25)26/h1-7H,(H2,19,25,26)(H3,18,20,21,22)
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| InChIKey |
KDKUVYLMPJIGKA-UHFFFAOYSA-N
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| CAS Number |
CAS 443797-96-4
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| PubChem Compound ID | ||||
| PubChem Substance ID |
8036422, 11062401, 12015752, 15174185, 39303404, 50100105, 51710589, 99437050, 103459325, 103905616, 113916272, 124756117, 124757114, 125163918, 125749047, 126728322, 131480738, 134343899, 135685408, 135685409, 135685428, 136340238, 136367371, 136367910, 136920341, 137275995, 142802375, 143498411, 144116095, 152234900, 152258176, 152344088, 160647013, 162011815, 162037517, 162202611, 162527774, 163410374, 163848324, 164193991, 170482001, 172113491, 172914002, 174561024, 177748752, 178102555, 180386842, 186007036, 188899536, 198980347
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| ChEBI ID |
CHEBI:94506
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| References | Top | |||
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| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5932). | |||
| REF 2 | Synthesis and evaluation of N-acyl sulfonamides as potential prodrugs of cyclin-dependent kinase inhibitor JNJ-7706621. Bioorg Med Chem Lett. 2006 Jul 15;16(14):3639-41. | |||
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