Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D03HVV
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| Former ID |
DIB006716
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| Drug Name |
Efaproxyn
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| Synonyms |
Efaproxiral; RSR13
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| Drug Type |
Small molecular drug
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| Indication | Lung cancer [ICD-11: 2C25.0; ICD-9: 162] | Phase 3 | [1] | |
| Company |
Allos Therapeutics
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| Structure |
 |
Download2D MOL |
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| Formula |
C20H23NO4
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| Canonical SMILES |
CC1=CC(=CC(=C1)NC(=O)CC2=CC=C(C=C2)OC(C)(C)C(=O)O)C
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| InChI |
1S/C20H23NO4/c1-13-9-14(2)11-16(10-13)21-18(22)12-15-5-7-17(8-6-15)25-20(3,4)19(23)24/h5-11H,12H2,1-4H3,(H,21,22)(H,23,24)
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| InChIKey |
BNFRJXLZYUTIII-UHFFFAOYSA-N
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| CAS Number |
CAS 131179-95-8
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| PubChem Compound ID | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | ClinicalTrials.gov (NCT00083304) Whole Brain Radiation Therapy With Oxygen, With or Without RSR13, in Women With Brain Metastases From Breast Cancer. U.S. National Institutes of Health. | |||
| REF 2 | Increased oxygenation of intracranial tumors by efaproxyn (efaproxiral), an allosteric hemoglobin modifier: In vivo EPR oximetry study. Int J Radiat Oncol Biol Phys. 2005 Apr 1;61(5):1503-9. | |||
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