Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D02VPC
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| Former ID |
DNC000086
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| Drug Name |
5-hydroxy-1H-indole-3-acetic acid
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| Synonyms |
5-Hydroxyindole-3-acetic acid; 54-16-0; 5-HIAA; 2-(5-hydroxy-1H-indol-3-yl)acetic acid; 5-Hydroxyindoleacetic acid; 5-Hydroxyheteroauxin; (5-Hydroxy-1H-indol-3-yl)acetic acid; 5-Oxyindoleacetic acid; 5-Hydroxy-IAA; 5-Hydroxyindolacetic acid; 5-Hydroxy-3-indoleacetic acid; 5-Hydroxyindol-3-ylacetic acid; Hydroxyindoleacetic acid; 5-Hydroxy-1H-indole-3-acetic acid; 5-Hydroxyindolylacetic acid; 1H-Indole-3-acetic acid, 5-hydroxy-; 1321-73-9; Indole-3-acetic acid, 5-hydroxy-; 5-Hydroxyindoleacetate; UNII-YHC763JY1P; NSC 90432
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C10H9NO3
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| Canonical SMILES |
C1=CC2=C(C=C1O)C(=CN2)CC(=O)O
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| InChI |
1S/C10H9NO3/c12-7-1-2-9-8(4-7)6(5-11-9)3-10(13)14/h1-2,4-5,11-12H,3H2,(H,13,14)
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| InChIKey |
DUUGKQCEGZLZNO-UHFFFAOYSA-N
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| CAS Number |
CAS 54-16-0
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| PubChem Compound ID | ||||
| PubChem Substance ID |
7946, 397247, 3133455, 5491791, 8151302, 10506683, 11111285, 11160881, 11448923, 15042342, 17405197, 24278130, 25622124, 29221025, 46500482, 48035330, 48259440, 49747725, 49983212, 50106443, 50106444, 51074946, 53777742, 53795932, 53837810, 57321040, 57566911, 57639082, 78096039, 81058741, 85086791, 85086792, 85165160, 85231079, 87570770, 90340656, 90451705, 92297567, 92304020, 93579330, 99373880, 103145395, 103530353, 103771595, 104298836, 107929593, 117357070, 118047416, 121361438, 124561183
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| ChEBI ID |
CHEBI:27823
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | DNA topoisomerase I (TOP1) | Target Info | Binder | [1] |
| NetPath Pathway | IL2 Signaling Pathway | |||
| Panther Pathway | DNA replication | |||
| Pathway Interaction Database | Caspase Cascade in Apoptosis | |||
| WikiPathways | Integrated Pancreatic Cancer Pathway | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Comparison of responses of DNA topoisomerase I from Candida albicans and human cells to four new agents which stimulate topoisomerase-dependent DNA nicking. FEMS Microbiol Lett. 1996 May 1;138(2-3):105-11. | |||
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